"Pirates of the Caribbean: On Stranger Tides" (May 20)
Sequel/remake/adaptation? Fourth film in a franchise based on Disney's theme park attraction
In 3D? Yes (also in IMAX)
What's at stake: The first three "Pirates" movies were conceived as a trilogy, but Disney—and Johnny Depp—didn't want to let Jack Sparrow go. So he's back, with a new director—Rob Marshall ("Chicago")—and a mysterious new love interest played by Penélope Cruz.
Chance of success: The second "Pirates" movie brought in over $1 billion worldwide and the third nearly matched it. Even if Captain Jack's fourth adventure earned only half that bounty, it would easily be one of the year's biggest hits.